What is the difference between an F-bottom and a U-bottom 96 well plate?

The F Bottom style is flat, while the U bottom style is U shaped. The flat bottom style generally has a larger well capacity - for the 96-Well Plate cellGrade Polystyrene Sterile with Lids the flat bottom capacity is 350 uL versus the U bottom at 330 uL. The bottom style may also effect the compatibility of the plate with the equipment being utilized.
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